If you have an issue with drag queens, then Charlize Theron will come for you.

Charlize Theron promises to 'f**k up' anybody who is against drag queens

And, If you’ve seen Mad Max: Fury Road or Atomic Blonde, then you’ll know the South African-American actor is not one to be messed with.

She made her thoughts clear in a pre-recorded clip that was played at the Drag Isn’t Dangerous telethon fundraiser.

“We’ve got you and I will f***k anybody up who’s trying to f***k… with you guys,” the Bombshell star said.

“In all seriousness, there [are] so many things that are hurting and really killing our kids, and we all know what I’m talking about right now, and it ain’t no drag queen.

“If you’ve ever seen a drag queen lip sync for her life, it only makes you happier.”

She added: “We love you queens.”

Theron’s message comes as bills in 14 US states are currently being fashioned to see hate and stigma towards LGBTQ people, specifically drag queens in some cases, legalized.

Some legislation even aims to prevent drag queens from being anywhere near kids in the same way a child sex offender would be made to avoid them.

Saturday Night Live’s Leslie Jones, openly bisexual comedian Margaret Cho, and comedian and actor Sarah Silverman were just a few of the big names from Hollywood who are now using their voices to call for protections for queer Americans.

Jones made her feelings about the issue clear, sending a stark warning to lawmakers: “Drag isn’t dangerous, but Leslie Jones is.”

Cho added: “Drag brings hope, truth and laughter to a community that desperately needs it. We need to fight for drag rights because we need to fight for gay rights, for our rights.”

Silverman then quipped that she would ‘trust RuPaul before any [Republican] hate mongers’, adding if they ‘come for you [drag artists], they will have to come through me first’.

RuPaul’s Drag Race judge Michelle Visage spoke to PinkNews about how absurd it is that a telethon to protect drag queens is even needed in our modern age.

“I wish I could say that I’m glad to be here, but I am appalled I have to be at something called Drag Isn’t Dangerous,” she said.

“Imagine a world where dancers are told they can’t dance, imagine a world where artists are told they cannot take paint to canvas… because it’s ‘bad for children’.

“That is what is happening to drag right now.”

The campaign aims to show that drag performers are not dangerous child groomers, sexual deviants, criminals or anything other than entertainers and artists.

The GoFundMe drive has raised more than USD$587,166 (AUD$866,921, £465,282) at the time of writing, with the money to be split between several LGBTQ+ charities across America.